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NFKBIA Antibody
Instruction Manual!
| Product name: | NFKBIA Antibody |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-NFKBIA Antibody - N-terminal region
Catalog Number：IC105166
Product Profile
| ProductName | Rabbit anti-NFKBIA Antibody - N-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for Anti-NFKBIA antibody is: synthetic peptide directed towards the N-terminal region of Human NFKBIA |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | NFKBIA |
|---|---|
| Gene Synonyms |
IKBA
MAD-3 NFKBI |
| Gene Summary |
NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).
More
|
| Alternative Names |
IKBA
MAD-3 NFKBI |
| MolecularWeight(MW) | 35kDa |
| Sequence | 317 amino acids |
Database Links
| Entrez Gene | 4792 |
|---|---|
| SwissProt ID | P25963 |
| Protein Accession | NP_065390 |
Application
-
Western blot
Host: Rabbit
Target Name: NFKBIA
Sample Tissue: Hela Whole Cell lysates
Antibody Dilution: 1.0ug/ml
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
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