OAS1 antibody
Product name: | OAS1 antibody |
Source: | Rabbit |
Purity: | >95% |
Buffer Formulation: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Applications: | WB IHC |
Storage: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
UOM: | 100ug |
Rabbit anti-OAS1 polyclonal antibody - C-terminal region
Catalog Number:IC105213
Product Profile
Product Name | Rabbit anti-OAS1 polyclonal antibody - C-terminal region |
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Antibody Type | Primary Antibodies |
Key Feature
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Target Information
Gene Symbol | OAS1 |
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Gene Synonyms |
IFI-4
OIAS OIASI |
Gene Full Name | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
Gene Summary |
OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Mutations in this gene have been associated with host susceptibility to viral infection.
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Alternative Names |
IFI-4
OIAS OIASI |
MolecularWeight(MW) | 46kDa |
Sequence | 400 amino acids |
Database Links
Entrez Gene | 4938 |
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SwissProt ID | P00973 |
Application
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Immunohistochemistry
Immunohistochemistry with Small intestine tissue at an antibody concentration of 5ug/ml using anti-OAS1 antibody
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Western blot
1 ug/ml
Positive Control: HepG2 cell lysate
Additional Information
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.