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N-Myc Antibody (H-50)
Instruction Manual!
| Product name: | N-Myc Antibody (H-50) |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB, IP, IF, ELISA |
| Storage: | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| UOM: | 100ug |
N-Myc Antibody (H-50)
Catalog Number：IC173713
Product Profile
| ProductName | N-Myc Antibody (H-50) |
|---|---|
| AntibodyType | Tags Antibodies |
| ModificationNotes | The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas (1), and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc (2). Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines (3,5). The extent of N-Myc amplification correlates well with the stage of neuroblastoma disease (4). Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein (2) that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein designated Max (5-7). |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
|
recommended for detection of N-Myc of human origin by WB, IP, IF and ELISA:
|
|
| Species Reactivity | |
| Concentration | 200 µg/ml |
| Purification | Affinity purified |
Target Information
| AlternativeNames |
epitope corresponding to amino acids 136-185 mapping near the N-terminus of N-Myc of human origin
|
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 136-185 mapping near the N-terminus of N-Myc of human origin |
Database Links
| Entrez Gene | 4613 |
|---|
Application
| Application Notes |
recommended for detection of N-Myc of human origin by WB, IP, IF and ELISA:
|
|---|
Additional Information
| Form | Liquid |
|---|---|
| StorageInstructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
