L-Myc Antibody (H-44)
Product name: | L-Myc Antibody (H-44) |
Source: | Rabbit |
Purity: | >95% |
Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Applications: | WB, IP, IF, ELISA |
Storage: | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
UOM: | 100ug |
L-Myc Antibody (H-44)
Catalog Number:IC176265
Product Profile
ProductName | L-Myc Antibody (H-44) |
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AntibodyType | Tags Antibodies |
ModificationNotes | The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. The extent of N-Myc amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 minute) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.designated Max. |
Key Feature
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
recommended for detection of L-Myc-1 and, to a lesser extent, L-Myc-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine:
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SpeciesReactivity | |
Concentration | 200 µg/ml |
Purification | Affinity purified |
Target Information
Alternative Names |
epitope corresponding to amino acids 321-364 of L-Myc-1 of human origin
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Tissue Specificity | epitope corresponding to amino acids 321-364 of L-Myc-1 of human origin |
Database Links
Entrez Gene | 4610 |
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Application
ApplicationNotes |
recommended for detection of L-Myc-1 and, to a lesser extent, L-Myc-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine:
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Additional Information
Form | Liquid |
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StorageInstructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.