elisa kit elisa kits logo

Tel:631-424-0089
Fax:631-424-0095
Email: info@immunoclone.com

Home>>Products >>  New Products

p53 (phospho Ser392) Antibody

p53 (phospho Ser392) Antibody p53 (phospho Ser392) Antibody

Instruction Manual!

Product name: p53 (phospho Ser392) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

p53 (phospho Ser392) Antibody

Catalog Number:IC287193

Product Profile

Product Name p53 (phospho Ser392) Antibody
Antibody Type Primary Antibodies
Productdescription
							
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.1) Choi DW, et al. (2013) Mol Cell 51, 374-85
More 
Immunogen
p53 (phospho Ser392) antibody was raised against a peptide sequence around phosphorylation site of serine 392 (P-D-S (p)-D) derived from Human p53.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

Human

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol TP53
Alternative Names
Antigen NY-CO-13
Cellular tumor antigen p53
Phosphoprotein p53
TP53
Tumor suppressor p53
More 
MolecularWeight(MW)  53 kDa
Tissue Specificity The antibody detects endogenous level of p53 only when phosphorylated at serine 392.

Database Links

Entrez Gene 7157
Protein Accession NP_000537.3

Application

  • Application

    Western blot analysis of extracts from 293 cells treated with Etoposide using Phospho-p53 (Ser392) Antibody. The lane on the right is treated with the antigen-specific peptide.

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

Copyright @ USA Immuno Clone Co., Ltd(I&C) All Rights Reserved Language:Chinese