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FAK (phospho Ser843) Antibody

FAK (phospho Ser843) Antibody FAK (phospho Ser843) Antibody

Instruction Manual!

Product name: FAK (phospho Ser843) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

FAK (phospho Ser843) Antibody

Catalog Number:IC278446

Product Profile

Product Name FAK (phospho Ser843) Antibody
Antibody Type Primary Antibodies
Productdescription 
							
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.1) Jiang X, Sinnett-Smith J, Rozengurt E (2007)Cell Signal 19, 1000-10 . Jacamo R, Jiang X, Lunn JA, Rozengurt E (2007)J Cell Physiol 210, 436-44. Le Boeuf F, Houle F, Sussman M, Huot J (2006)Mol Biol Cell 17, 3508-20 .
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Immunogen
FAK (phospho Ser843) antibody was raised against a peptide sequence around phosphorylation site of serine843 (R-G-S (p)-I-D) derived from Human FAK .

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol PTK2
Alternative Names
FADK 1
FAK1
Focal adhesion kinase 1
PTK2
pp125FAK
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MolecularWeight(MW)  120 kDa
Tissue Specificity The antibody detects endogenous level of FAK only when phosphorylated at serine 843.

Database Links

Entrez Gene 5747
Protein Accession NP_001186578.1

Application

  • Application

    Western blot analysis of extracts from HepG2 cells treated with PMA using Phospho-FAK (Ser843) Antibody. The lane on the right is treated with the antigen-specific peptide.

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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