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Retinoblastoma (phospho Ser608) Antibody

Retinoblastoma (phospho Ser608) Antibody Retinoblastoma (phospho Ser608) Antibody

Instruction Manual!

Product name: Retinoblastoma (phospho Ser608) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:IHCWB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

Retinoblastoma (phospho Ser608) Antibody

Catalog Number:IC289835

Product Profile

Product Name Retinoblastoma (phospho Ser608) Antibody
Antibody Type Primary Antibodies
Productdescription
							
Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.1) Lee W.-H., Nature 329:642-645(1987).
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Immunogen
Retinoblastoma (phospho Ser608) antibody was raised against a peptide sequence around phosphorylation site of Serine 608 (Y-L-S (p)-P-V) derived from Human Retinoblastoma.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHCWB

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Species Reactivity

HumanMouse

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol RB1
Alternative Names
P105-RB
PP105
PP110
RB1
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MolecularWeight(MW)  110 kDa
Tissue Specificity The antibody detects endogenous levels of Retinoblastoma only when phosphorylated at serine 608.

Database Links

Entrez Gene 5925
Protein Accession NP_000312.2

Application

  • Application

    Immunohistochemical analysis of paraffin-embedded human brain tissue using Retinoblastoma (Phospho-Ser608) antibody (left) or the same antibody preincubated with blocking peptide (right).

  • Application

    Western blot analysis of extracts from JK cells (Lane 2), using Retinoblastoma (Phospho-Ser608) Antibody. The lane on the left is treated with antigen-specific peptide.

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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