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ATF-2 (phospho Ser472) Antibody

ATF-2 (phospho Ser472) Antibody ATF-2 (phospho Ser472) Antibody

Instruction Manual!

Product name: ATF-2 (phospho Ser472) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:IHC
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

ATF-2 (phospho Ser472) Antibody

Catalog Number:IC271795

Product Profile

Product Name ATF-2 (phospho Ser472) Antibody
Antibody Type Primary Antibodies
Productdescription
							
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.1) Maekawa T., EMBO J. 8:2023-2028(1989).
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Immunogen
ATF-2 (phospho Ser472) antibody was raised against a peptide sequence around phosphorylation site of Serine 472 (E-A-V (p)-A-T) derived from Human ATF-2.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC

Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol ATF2
Alternative Names
Activating 2
ATF2
cAMP response element binding protein CRE- BP1
CREB2
HB16
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MolecularWeight(MW)  54 kDa
Tissue Specificity The antibody detects endogenous levels of ATF-2 only when phosphorylated at serine 472.

Database Links

Entrez Gene 1386
Protein Accession NP_001243019.1

Application

  • Application

    Immunohistochemical analysis of paraffin-embedded human brain tissue using ATF-2 (Phospho-Ser472) antibody (left) or the same antibody preincubated with blocking peptide (right).

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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