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RAF1 Antibody

RAF1 Antibody RAF1 Antibody

Instruction Manual!

Product name: RAF1 Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:PBS, 0.02% sodium azide, 50% glycerol.
Applications:IHCWB
Storage:RAF1 antibody should be stored long term (months) at -80 ˚C and short term (days) at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
UOM:100ug

RAF1 Antibody

Catalog Number:IC289472

Product Profile

Product Name RAF1 Antibody
Antibody Type Primary Antibodies
Productdescription
							
RAF, a member of the Raf Subfamily of Serine/Threonine Protein Kinases, is part of the RAS-dependent signalling pathway. Once activated, Raf-1 can activate the dual specificity protein kinases MEK1 and MEK2 which in turn activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. t(3;8)(p25;q21) translocations involving RAF1 result in mixed parotid gland tumors. Raf1 is an ocogene that has been reported to be overexpressed in many tumor types.
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Immunogen
RAF1 antibody was raised against amino acids surrounding Ser 259 of RAF1 (Human).

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
TestedApplications 

IHCWB

RAF1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200.:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol RAF1
Alternative Names
RAF1
C-Raf
C-raf-1
CRAF
NS5
Raf-1
Proto-oncogene c-RAF
Oncogene RAF1
RAF
Raf1 kinase
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Tissue Specificity pSer259

Database Links

Entrez Gene 5894
Protein Accession P04049

Application

  • Application

    Immunohistochemistry staining of RAF1 in kidney tissue using RAF1 Antibody.

ApplicationNotes 
RAF1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200.:

Additional Information

Form Liquid
StorageInstructions  RAF1 antibody should be stored long term (months) at -80 ˚C and short term (days) at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer PBS, 0.02% sodium azide, 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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