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CREB (phospho Ser129) Antibody

CREB (phospho Ser129) Antibody CREB (phospho Ser129) Antibody

Instruction Manual!

Product name: CREB (phospho Ser129) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:IHCWB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

CREB (phospho Ser129) Antibody

Catalog Number:IC276093

Product Profile

Product Name CREB (phospho Ser129) Antibody
Antibody Type Primary Antibodies
Productdescription
							
This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.1) Chrystelle V. Garat, et al. (2006) Mol. Cell. Biol ; 26: 4934 - 4948. Lilah Rothem, et al. (2004) Mol. Pharmacol ; 66: 1536 - 1543. Darren R. Tyson, et, al. (2002) Endocrinology; 143: 674. Kyung-Woo Park, et al. (2003) Arterioscler. Thromb. Vasc. Biol ; 23: 1364.
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Immunogen
CREB (Phospho-Ser129) antibody was raised against a peptide sequence around phosphorylation site of serine 129 (I-L-S (p) -R-R) derived from Human CREB.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IHCWB

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol CREB1
Alternative Names
CREB
HSP90B
HSPC2
HSPCB
CREB-1
CREB1
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Molecular Weight(MW) 43 kDa
Tissue Specificity This antibody detects endogenous level of CREB only when phosphorylated at serine 129.

Database Links

Entrez Gene 1385
Protein Accession NP_004370.1

Application

  • Application

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CREB (Phospho-Ser129).

  • Application

    Western blot analysis of lysed extracts from 293 cells untreated (Lane 1) or treated with UV (lane 2) using CREB (Phospho-Ser129).

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

Additional Information

Form Liquid
StorageInstructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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