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IRS 1 Antibody

IRS 1 Antibody IRS 1 Antibody

Instruction Manual!

Product name: IRS 1 Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

IRS 1 Antibody

Catalog Number:IC282335

Product Profile

Product Name IRS 1 Antibody
Antibody Type Primary Antibodies
Productdescription 
							
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit1) Tzatsos A, et al. (2006) Mol Cell Biol; 26 (1): 63-76Kadowaki T, et al. (2000) J Clin Invest; 106 (4): 459-465Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98 (8): 4640-4645Szanto I, et al. (2000) Proc Natl Acad Sci U S A; 97 (5): 2355-2360
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Immunogen
IRS-1 (Ab-639) antibody was raised against a peptide sequence around aa.637~641 (P-K-S-V-S) derived from Human IRS-1.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Species Reactivity

Human

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol IRS1
Alternative Names
HIRS-1
MAPTL
MTBT1
TAU
IRS-1
IRS1
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Molecular Weight(MW) 180 kDa
Tissue Specificity This antibody detects endogenous level of total IRS-1 protein.

Database Links

Entrez Gene 3667
Protein Accession NP_005535.1

Application

  • Application

    Immunofluorescence staining of methanol-fixed HeLa cells using IRS-1 (Ab-639).

  • Application

    Western blot analysis of lysed extracts from HT29 and 3T3 cells using IRS-1 (Ab-639).

Application Notes
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:

Additional Information

Form Liquid
StorageInstructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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