elisa kit elisa kits logo

Tel:631-424-0089
Fax:631-424-0095
Email: info@immunoclone.com

Home>>Products >>  New Products

BAD (phospho Ser136) Antibody

BAD (phospho Ser136) Antibody BAD (phospho Ser136) Antibody

Instruction Manual!

Product name: BAD (phospho Ser136) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:IHCWB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

BAD (phospho Ser136) Antibody

Catalog Number:IC272162

Product Profile

Product Name BAD (phospho Ser136) Antibody
Antibody Type Primary Antibodies
Productdescription 
							
The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.1) Wang XQ, et al. (2001) . J Biol Chem. 276 (48): 44504-44511. Lee YI, et al. (2001) . J Biol Chem. 276 (20): 16969-16977. Maiti D, et al. (2001) . J Biol Chem. 276 (1): 329-333.
More 
Immunogen
BAD (Phospho-Ser136) antibody was raised against a peptide sequence around phosphorylation site of serine136 (S-R-S (p) -A-P) derived from Mouse BAD.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IHCWB

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Species Reactivity

Mouse

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol BAD
Alternative Names
BBC2
BCL2L8
BBC6
More 
Molecular Weight(MW) 23 kDa
Tissue Specificity This antibody detects endogenous level of BAD only when phosphorylated at serine136.

Database Links

Entrez Gene 572
Protein Accession NP_004313.1

Application

  • Application

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BAD (Phospho-Ser136).

  • Application

    Western blot analysis of lysed extracts from HT29 cells untreated or treated with UV using BAD (Phospho-Ser136).

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

Copyright @ USA Immuno Clone Co., Ltd(I&C) All Rights Reserved Language:Chinese