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VEGFR2 (phospho Tyr951) Antibody

VEGFR2 (phospho Tyr951) Antibody VEGFR2 (phospho Tyr951) Antibody

Instruction Manual!

Product name: VEGFR2 (phospho Tyr951) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:IFIHCWB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

VEGFR2 (phospho Tyr951) Antibody

Catalog Number:IC294901

Product Profile

Product Name VEGFR2 (phospho Tyr951) Antibody
Antibody Type Primary Antibodies
Productdescription 
							
Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions1) Zeng H, et al. (2001) J Biol Chem. 276 (35): 32714-32719. Dougher M, et al. (1999) Oncogene. 18 (8): 1619-1627.
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Immunogen
VEGFR2 (Phospho-Tyr951) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 951 (K-D-Y (p) -V-G) derived from Human VEGFR2.

Key Feature

Clonality Polyclonal
Host Species Rabbit
TestedApplications 

IFIHCWB

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol KDR
Alternative Names
FLK1
CD309
VEGFR
VEGFR2
HER3
FLK1
KDR
VGFR2
VGR2
kinase insert domain receptor
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MolecularWeight(MW)  230 kDa
Tissue Specificity This antibody detects endogenous level of VEGFR2 only when phosphorylated at tyrosine 951.

Database Links

Entrez Gene 3791
Protein Accession NP_002244.1

Application

  • Application

    Western blot analysis of lysed extracts from G-CSF-treated HUVEC and serum-treated HT29 cells using VEGFR2 (Phospho-Tyr951).

  • Application

    Top Image: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using VEGFR2 (Phospho-Tyr951). Bottom Image: Immunofluorescence staining of methanol-fixed MCF7 cells using VEGFR2 (Phospho-Tyr951).

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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