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Smad3 (phospho Ser425) Antibody

Smad3 (phospho Ser425) Antibody Smad3 (phospho Ser425) Antibody

Instruction Manual!

Product name: Smad3 (phospho Ser425) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:IHC
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

Smad3 (phospho Ser425) Antibody

Catalog Number:IC291657

Product Profile

Product Name Smad3 (phospho Ser425) Antibody
Antibody Type Primary Antibodies
Productdescription
							
Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.1) Shi W, et al. J Cell Sci. 2007 Apr 1;120 (Pt 7): 1216-24Seong HA, et al. J Biol Chem. 2007 Apr 20;282 (16): 12272-89Wordinger RJ, et al. Invest Ophthalmol Vis Sci. 2007 Mar;48 (3): 1191-200LeClair RJ, et al. Circ Res. 2007 Mar 30;100 (6): 826-33
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Immunogen
Smad3 (Phospho-Ser425) antibody was raised against a peptide sequence around phosphorylation site of serine 425 (C-S-S-V-S (p) ) derived from Human Smad3.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IHC

, Immunohistochemistry: 1:50~1:100:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol SMAD3
Alternative Names
LDS3
LDS1C
MADH3
JV15-2
HSPC193
HsT17436
PTP2C
SHPTP2
MAD-3
Mad3
Mothers against DPP homolog 3
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Molecular Weight(MW) 52 kDa
Tissue Specificity This antibody detects endogenous level of Smad3 only when phosphorylated at serine 425.

Database Links

Entrez Gene 4088
Protein Accession NP_001138574.1

Application

  • Application
  • Application

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Smad3 (Phospho-Ser425).

Application Notes
, Immunohistochemistry: 1:50~1:100:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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