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IGF1 Receptor Antibody

IGF1 Receptor Antibody IGF1 Receptor Antibody

Instruction Manual!

Product name: IGF1 Receptor Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Supplied in PBS with 0.09% (W/V) sodium azide.
Applications:IHC-PWB
Storage:Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
UOM:100ug

IGF1 Receptor Antibody

Catalog Number:IC281719

Product Profile

Product Name IGF1 Receptor Antibody
Antibody Type Primary Antibodies
Productdescription
							
The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.1) Song, R.X., et al., Proc. Natl. Acad. Sci. U.S.A. 101(7):2076-2081 (2004).
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Immunogen
This IGF1 Receptor (IGF1R) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-51 amino acids from the N-terminal region of human IGF1 Receptor (IGF1R).

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

IHC-PWB

For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:50~100:
Species Reactivity

Human

Concentration 1mg/ml
Purification Unpurified

Target Information

Gene Symbol IGF1R
Alternative Names
Insulin-like growth factor 1 receptor
Insulin-like growth factor I receptor
IGF-I receptor
CD221
Insulin-like growth factor 1 receptor alpha chain
Insulin-like growth factor 1 receptor beta chain
IGF1R
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Molecular Weight(MW) 155 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Mouse

Database Links

Entrez Gene 3480
Protein Accession P08069

Application

  • Application

    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma.

  • Application

    Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: A549 whole cell lysate Lysates/proteins at 20 ug per lane.

Application Notes
For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:50~100:

Additional Information

Form Liquid
StorageInstructions  Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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