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IGF 1R (phospho Tyr1165 / Tyr1166) Antibody

IGF 1R (phospho Tyr1165 / Tyr1166) Antibody IGF 1R (phospho Tyr1165 / Tyr1166) Antibody

Instruction Manual!

Product name: IGF 1R (phospho Tyr1165 / Tyr1166) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:IFWB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

IGF 1R (phospho Tyr1165 / Tyr1166) Antibody

Catalog Number:IC281704

Product Profile

Product Name IGF 1R (phospho Tyr1165 / Tyr1166) Antibody
Antibody Type Primary Antibodies
Productdescription
							
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.1) Li S, et al. (1994) J Biol Chem; 269 (51): 32558-64.
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Immunogen
IGF-1R (Phospho-Tyr1165/Tyr1166) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1165/tyrosine 1166 (T-D-Y (p) -Y (p) -R-K) derived from Human IGF-1R .

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IFWB

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol IGF1R
Alternative Names
IGFR
CD221
IGFIR
JTK13
RAB5
Insulin-like growth factor I receptor
IGF1R
kinase IGF1R
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MolecularWeight(MW)  200, 95 kDa
Tissue Specificity This antibody detects endogenous level of IGF-1R onlywhen phosphorylated at tyrosine 1165/tyrosine1166.

Database Links

Entrez Gene 3480
Protein Accession NP_000866.1

Application

  • Application

    Immunofluorescence staining of methanol-fixed MCF cells using IGF-1R (Phospho-Tyr1165/Tyr1166).

  • Application

    Western blot analysis of lysed extracts from 293 cells untreated or treated with insulin using IGF-1R (Phospho-Tyr1165/Tyr1166).

Application Notes
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:

Additional Information

Form Liquid
Storagenstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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