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Tyrosine Hydroxylase Antibody

Tyrosine Hydroxylase Antibody Tyrosine Hydroxylase Antibody

Instruction Manual!

Product name: Tyrosine Hydroxylase Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
Applications:IFIHCWB
Storage:Tyrosine Hydroxylase antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year.
UOM:100ug

Tyrosine Hydroxylase Antibody

Catalog Number:IC294460

Product Profile

Product Name Tyrosine Hydroxylase Antibody
Antibody Type Primary Antibodies
Productdescription 
							
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001; Dunkley et al., 2004).1) Dunkley PR, Bobrovskaya L, Graham ME, Von Nagy-Felsobuki EI, Dickson PW (2004) Tyrosine hydroxylase phosphorylation: regulation and consequences. J Neurochem 91:1025-1043.
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Immunogen
SDS-denatured rat tyrosine hydroxylase, purified from pheochromocytoma.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IFIHCWB

Species Reactivity

Mammalian species

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol Th
Alternative Names
The
Tyrosine 3-hydroxylase
TH
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Molecular Weight(MW) 60
Tissue Specificity Specific for the ~60k tyrosine hydroxylase protein.

Database Links

Entrez Gene 25085
Protein Accession P04177

Application

  • Application

    Western blot of 10 ug of rat caudate lysate showing specific immunolabeling of the ~60k TH protein.

Additional Information

Form Liquid
StorageInstructions  Tyrosine Hydroxylase antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year.
Storage Buffer 100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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