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Tyrosine Hydroxylase (phospho Ser40) Antibody

Tyrosine Hydroxylase (phospho Ser40) Antibody Tyrosine Hydroxylase (phospho Ser40) Antibody

Instruction Manual!

Product name: Tyrosine Hydroxylase (phospho Ser40) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:IF
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

Tyrosine Hydroxylase (phospho Ser40) Antibody

Catalog Number:IC294458

Product Profile

Product Name Tyrosine Hydroxylase (phospho Ser40) Antibody
Antibody Type Primary Antibodies
Productdescription 
							
The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.1) Vazin T, et al. Stem Cells. 2008 Jun;26 (6): 1517-25Pistocchi A, et al. BMC Dev Biol. 2008 Mar 10;8:27 Fukakusa A, et al. J Pharmacol Sci. 2008 Feb;106 (2): 321-4.
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Immunogen
Tyrosine Hydroxylase (Phospho-Ser40) antibody was raised against a peptide sequence around phosphorylation site of serine 40 (R-Q-S (p) -L-I) derived from Human Tyrosine Hydroxylase (TH).

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IF

Immunofluorescence: 1:100~1:200:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol TH
Alternative Names
TYH
DYT14
DYT5b
MAPTL
MTBT1
TAU
TY3H
TYH
Tyrosine 3-hydroxylase
tyrosine hydroxylase
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MolecularWeight(MW)  55 - 60 kDa
Tissue Specificity This antibody detects endogenous level of TyrosineHydroxylase only when phosphorylated at serine 40.

Database Links

Entrez Gene 7054
Protein Accession NP_000351.2

Application

  • Application

    Immunofluorescence staining of methanol-fixed HeLa cells using Tyrosine Hydroxylase (Phospho-Ser40).

Application Notes
Immunofluorescence: 1:100~1:200:

Additional Information

Form Liquid
StorageInstructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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