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ZAP70 antibody - N-terminal region
Instruction Manual!
| Product name: | ZAP70 antibody - N-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-ZAP70 polyclonal antibody - N-terminal region
Catalog Number：IC118735
Product Profile
| ProductName | Rabbit anti-ZAP70 polyclonal antibody - N-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-ZAP70 antibody: synthetic peptide directed towards the N terminal of human ZAP70 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | ZAP70 |
|---|---|
| Gene Synonyms |
FLJ17670
More
FLJ17679 SRK STD TZK ZAP-70 |
| Gene Full Name | Zeta-chain (TCR) associated protein kinase 70kDa |
| Gene Summary |
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
More
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| Alternative Names |
FLJ17670
More
FLJ17679 SRK STD TZK ZAP-70 |
| MolecularWeight(MW) | 34kDa |
| Sequence | 312 amino acids |
Database Links
| Entrez Gene | 7535 |
|---|---|
| SwissProt ID | P43403 |
| Protein Accession | NP_997402 |
Application
-
Western blot
Titration: 1.0 ug/ml
Positive Control: Fetal Lung
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
