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FGFR1/2 (phospho Tyr463/466) Antibody

FGFR1/2 (phospho Tyr463/466) Antibody FGFR1/2 (phospho Tyr463/466) Antibody

Instruction Manual!

Product name: FGFR1/2 (phospho Tyr463/466) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

FGFR1/2 (phospho Tyr463/466) Antibody

Catalog Number:IC278820

Product Profile

Product Name FGFR1/2 (phospho Tyr463/466) Antibody
Antibody Type Primary Antibodies
Productdescription 
							
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.1) Itoh N., Biochem. Biophys. Res. Commun. 169:680-685(1990).
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Immunogen
FGFR1/2 (phospho Tyr463/466) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 463/466 (S-E-Y (p)-E-L) derived from Human FGFR1/2.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Species Reactivity

HumanMouse

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol FGFR1, FGFR2
Alternative Names
BFGFR
CEK
FLG
CD331
FLT2
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MolecularWeight(MW)  91 kDa
Tissue Specificity The antibody detects endogenous levels of FGFR1/2 only when phosphorylated at tyrosine 463/466.

Database Links

Entrez Gene 2260/2263
Protein Accession NP_075598.2

Application

  • Application

    Western blot analysis of extracts from HepG2 cells using FGFR1/2 (Phospho-Tyr463/466) Antibody. The lane on the right is treated with the antigen-specific peptide.

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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