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a Synuclein (phospho Ser129) Antibody

a Synuclein (phospho Ser129) Antibody a Synuclein (phospho Ser129) Antibody

Instruction Manual!

Product name: a Synuclein (phospho Ser129) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

a Synuclein (phospho Ser129) Antibody

Catalog Number:IC269450

Product Profile

Product Name a Synuclein (phospho Ser129) Antibody
Antibody Type Primary Antibodies
Productdescription
							
May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.1) Takahashi T, et al. J Biol Chem 2003 Oct 24; 278 (43): 42225-33Ahn BH, et al. J Biol Chem 2002 Apr 05; 277 (14): 12334-42Negro A, et al. FASEB J 2002 Feb; 16 (2): 210-2Goldberg, et al. Nat. Cell Biol. 2000; 2, 115-119.
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Immunogen
a-Synuclein (Phospho-Ser129) antibody was raised against a peptide sequence around phosphorylation site of serine 129 (M-P-S (p) -E-E) derived from Human α-Synuclein.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol SNCA
Alternative Names
PD1
NACP
PARK1
PARK4
ERBB
ERBB1
HER1
SYN
SYUA
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MolecularWeight(MW)  18 kDa
Tissue Specificity This antibody detects endogenous level of VEGFR2 only when phosphorylated at tyrosine 1214.

Database Links

Entrez Gene 6622
Protein Accession NP_000336.1

Application

  • Application

    Western blot analysis of lysed extracts from mouse brain tissue using α-Synuclein (Phospho-Ser129).

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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