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APP antibody - middle region
Instruction Manual!
| Product name: | APP antibody - middle region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Note: The product is for research use only,not for use in diagnostic or therapeutic procedures. Catalog Number:OM105240 Price:$325.00 Discount Price Size: Store:In stock |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-APP polyclonal antibody - middle region
Catalog Number：IC106166
Product Profile
| ProductName | Rabbit anti-APP polyclonal antibody - middle region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-APP antibody: synthetic peptide directed towards the middle region of human APP |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | APP |
|---|---|
| Gene Synonyms |
AAA
More
ABETA ABPP AD1 APPI CTFgamma CVAP PN2 PN-II |
| Gene Full Name | Amyloid beta (A4) precursor protein |
| Gene Summary |
APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
More
|
| Alternative Names |
AAA
More
ABETA ABPP AD1 APPI CTFgamma CVAP PN2 PN-II |
| MolecularWeight(MW) | 85kDa |
| Sequence | 770 amino acids |
Database Links
| Entrez Gene | 351 |
|---|---|
| SwissProt ID | P05067 |
| Protein Accession | NP_000475 |
Application
-
Immunohistochemical
Sample Type :
Mouse hippo campus
Primary Antibody Dilution :
1:100
Secondary Antibody:
Anti-rabbit-HRP
Secondary Antibody Dilution:
1:300
Color/Signal Descriptions:
App: Red Nucleus: Blue
Gene Name:
APP
Submitted by:
Teresa Gunn -
Western blot
0.2-1 ug/ml
ELISA Titer: 1:2500
Positive Control: Human heart
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
