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Amyloid-Beta 11 Antibody

Amyloid-Beta 11 Antibody Amyloid-Beta 11 Antibody

Instruction Manual!

Product name: Amyloid-Beta 11 Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:ELISAIHCWB
Storage:For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
UOM:100ug

Amyloid-Beta 11 Antibody

Catalog Number:IC271046

Product Profile

Product Name Amyloid-Beta 11 Antibody
Antibody Type Primary Antibodies
Productdescription
							
							
Pyroglutamic acid truncated amyloid beta 11-40/42 may have a greater propensity to aggregate under physiological conditions. In addition, this pyrE modification has been implicated as the molecular species responsible for seeding larger oligomers of amyloid-β. Pyroglutamic acid truncated amyloid beta 11-40/42’s exact involvement in the pathophysiology of Alzheimer’s disease has not been established1) Schilling S, Lauber T, Schaupp M, Manhart S, Scheel E, Bohm G, Demuth HU. On the seeding and oligomerization of pGlu-amyloid peptides (in vitro). Biochemistry. 2006 Oct 17;45(41):12393-9
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Immunogen
A synthetic peptide corresponding to the N-terminus 11-pyro E start point.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAIHCWB

ELISA , Western (immuno) blotting (in testing), Immunostaining (in testing):
Species Reactivity

Human

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol APP
Alternative Names
Amyloid-Beta 11-pyrE
AAA
AD1
PN2
ABPP
APPI
CVAP
ABETA
PN-II
CTFgamma
A4
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Database Links

Entrez Gene 351
Protein Accession P05067

Application

Application Notes
ELISA , Western (immuno) blotting (in testing), Immunostaining (in testing):

Additional Information

Form Liquid
StorageInstructions  For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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