elisa kit elisa kits logo

Tel:631-424-0089
Fax:631-424-0095
Email: info@immunoclone.com

Home>>Products >>  New Products

SNCA Antibody

SNCA Antibody SNCA Antibody

Instruction Manual!

Product name: SNCA Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:SNCA antibody is supplied in PBS containing 0.02% sodium azide.
Applications:ELISAIFIHC-PWB
Storage:SNCA antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
UOM:100ug

SNCA Antibody

Catalog Number:IC291789

  • 1
  • 2

Product Profile

Product Name SNCA Antibody
Antibody Type Primary Antibodies
Productescription 
							
Alpha-Synuclein (SNCA) is a hallmark of Alzheimer’s disease (1,2). It is a cytoplasmic protein that is predominantly expressed in the central nervous system (2). SNCA reduces neuronal responsiveness to various apoptotic stimuli, leading to the decreased caspase-3 activation. SNCA may be involved in the regulation of dopamine release and transport and induces fibrillization of microtubule-associated protein tau (3). Defects in SNCA are associated with familial Parkinson’s disease (4,5).1) Ueda K, Fukushima H, Masliah E, et al. Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc. Natl. Acad. Sci. USA 1993; 90:11282-6.
More 
Immunogen
SNCA antibody was raised against a 19 amino acid peptide near the carboxy terminus of human SNCA. The immunogen is located within the last 50 amino acids of SNCA.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
TestedApplications 

ELISAIFIHC-PWB

SNCA antibody can be used for detection of SNCA by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.:
More 
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol SNCA
Alternative Names
SNCA Antibody: PD1
NACP
PARK1
PARK4
Alpha-synuclein
Non-A beta component of AD amyloid
More 
MolecularWeight(MW)  Predicted: 12 kDa Observed: 16 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Pig: (100%), Bovine: (100%)
Tissue Specificity SNCA antibody is human, mouse and rat reactive. At least three isoforms of SNCA are known to exist.

Database Links

Entrez Gene 6622
Protein Accession NP_000336

Application

  • Application

    Western blot analysis of 1 ng of recombinant human SNCA with SNCA antibody at 1 μg/ml.

  • Application

    Immunohistochemistry of SNCA in rat brain tissue with SNCA antibody at 5 μg/ml.

  • Application

    Immunofluorescence of SNCA in rat brain tissue with SNCA antibody at 20 μg/ml.

  • Application

    Western blot analysis of SNCA in mouse cerebellum tissue lysate with SNCA antibody at 1 μg/ml.

Positive Control 1) Cat. No. 1412 - Mouse Cerebellum Tissue Lysate
ApplicationNotes
S NCA antibody can be used for detection of SNCA by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.:
More 

Additional Information

Form Liquid
Storage Instructions SNCA antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Storage Buffer SNCA antibody is supplied in PBS containing 0.02% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

Copyright @ USA Immuno Clone Co., Ltd(I&C) All Rights Reserved Language:Chinese