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SNCA Antibody

SNCA Antibody SNCA Antibody

Instruction Manual!

Product name: SNCA Antibody
Source:Mouse
Purity:>95%
Buffer Formulation:Ascitic fluid containing 0.03% sodium azide.
Applications:ELISAIHCWB
Storage:SNCA monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
UOM:100ug

SNCA Antibody

Catalog Number:IC291790

Product Profile

Product Name SNCA Antibody
Antibody Type Primary Antibodies
Productescription
							
Alpha-synuclein (SNCA), with 140-amino acid protein (about 15 kDa), belongs to the synuclein family, which also includes beta- and gamma-synuclein. SNCA is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). SNCA is implicated in the regulation of dopamine release and transport. The triplication of the SNCA can cause Parkinson disease (PD) and diffuse Lewy body disease within the same kindred. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Immunohistochemistry for SNCA has become the histological technique of choice for the diagnosis for Parkinson's disease, Dementia with Lewy bodies and Multiple System Atrophy.1) J. Johnson, S. M. Hague, M. Hanson. Neurology, Aug 2004; 63: 554 – 556.
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Immunogen
Ni-NTA purified truncated recombinant SNCA expressed in E. Coli strain BL21 (DE3).

Key Feature

Clonality Monoclonal
Host Species Mouse
TestedApplications 

ELISAIHCWB

Western Blot:1:500 - 1:2,000 IHC(P):1:500 - 1:2,000 IHC(F):1:500 - 1:2,000 ELISA:Propose dilution 1:10,000 Determining optimal working dilutions by titration test.:
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Species Reactivity

Human

Concentration 1mg/ml
Purification

Target Information

Gene Symbol SNCA
Alternative Names
NACP
PARK1
Non-A beta component of AD amyloid
NACP
PD1
PARK4
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Database Links

Entrez Gene 6622
Protein Accession P37840

Application

  • Application

    Immunohistochemical analysis of paraffin - embedded human glioma tissue showing membrane location using SNCA antibody with DAB staining.

  • Application

    Western blot analysis using SNCA monoclonal antibody against truncated SNCA recombinant protein.

ApplicationNotes
 Western Blot:1:500 - 1:2,000 IHC(P):1:500 - 1:2,000 IHC(F):1:500 - 1:2,000 ELISA:Propose dilution 1:10,000 Determining optimal working dilutions by titration test.:
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Additional Information

Form Liquid
StorageInstructions  SNCA monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Ascitic fluid containing 0.03% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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