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SNCA antibody - middle region
Instruction Manual!
| Product name: | SNCA antibody - middle region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Note: The product is for research use only,not for use in diagnostic or therapeutic procedures. Catalog Number:OM105240 Price:$325.00 Discount Price Size: Store:In stock |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-SNCA polyclonal antibody - middle region
Catalog Number：IC110856
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Product Profile
| ProductName | Rabbit anti-SNCA polyclonal antibody - middle region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-SNCA antibody: synthetic peptide directed towards the middle region of human SNCA |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | SNCA |
|---|---|
| Gene Synonyms |
MGC110988
More
NACP PARK1 PARK4 PD1 |
| Gene Full Name | Synuclein, alpha (non A4 component of amyloid precursor) |
| Gene Summary |
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease.Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Two alternatively spliced transcripts of SNCA have been identified. Additional splicing may be present but the full-length nature of these variants has not been determined.
More
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| Alternative Names |
MGC110988
More
NACP PARK1 PARK4 PD1 |
| MolecularWeight(MW) | 11kDa |
| Sequence | 112 amino acids |
Database Links
| Entrez Gene | 6622 |
|---|---|
| SwissProt ID | P37840-2 |
| Protein Accession | NP_009292 |
Application
-
Western blot
Host: Rabbit
Target Name: NSUN6
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml -
Western blot
Host: Rabbit
Target Name: FAM46C
Sample Tissue: Human Fetal Liver
Antibody Dilution: 1.0ug/ml -
Western blot
0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
