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MEK1 (phospho Thr291) Antibody

MEK1 (phospho Thr291) Antibody MEK1 (phospho Thr291) Antibody

Instruction Manual!

Product name: MEK1 (phospho Thr291) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

MEK1 (phospho Thr291) Antibody

Catalog Number:IC284534

Product Profile

Product Name MEK1 (phospho Thr291) Antibody
Antibody Type Primary Antibodies
Productdescription 
							
							
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.1) Kevin D. Burroughs, et, al. (2003) Mol. Cancer Res ; 1: 312. Michael J. Piatelli, et, al. (2002) J. Biol. Chem ; 277: 12144 - 12150. Margaret M. Morgan, et, al. (2001) J. Immunol ; 167: 5708. Herbert Schramek, et, al. (2003) Am J Physiol Cell Physiol, ; 285: C652 - C661.
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Immunogen
MEK1 (Phospho-Thr291) antibody was raised against a peptide sequence around phosphorylation site of threonine 291 (P-R-T (p) -P-G derived from Human MEK1.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol MAP2K1
Alternative Names
CFC3
MEK1
MKK1
MAPKK1
PRKMK1
TYH
ERK activator kinase 1
MAP kinase kinase 1
MAP2K1
MAPK/ERK kinase 1
MAPKK 1
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MolecularWeight(MW)  45 kDa
Tissue Specificity This antibody detects endogenous level of MEK1 only when phosphorylated at threonine 291.

Database Links

Entrez Gene 5604
Protein Accession NP_002746.1

Application

  • Application

    Western blot analysis of lysed extracts from HepG2 cells untreated or treated with PMA using MEK1 (Phospho-Thr291).

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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