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SYK (phospho Tyr352) Antibody

SYK (phospho Tyr352) Antibody SYK (phospho Tyr352) Antibody

Instruction Manual!

Product name: SYK (phospho Tyr352) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

SYK (phospho Tyr352) Antibody

Catalog Number:IC292610

Product Profile

Product Name SYK (phospho Tyr352) Antibody
Antibody Type Primary Antibodies
Productdescription
							
Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion1) Yagi S., Biochem. Biophys. Res. Commun. 200:28-34(1994).
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Immunogen
SYK (phospho Tyr352) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 352 (S-P-Y (p)-A-D) derived from Human SYK.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol SYK
Alternative Names
SYK
KSYK
FLJ25043
FLJ37489
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Molecular Weight(MW) 72 kDa
Tissue Specificity The antibody detects endogenous levels of SYK only when phosphorylated at tyrosine 352.

Database Links

Entrez Gene 6850
Protein Accession NP_001167638.1

Application

  • Application

    Western blot analysis of extracts from HuvEc cells (Lane 2) and HepG2 cells (Lane 3), using SYK (Phospho-Tyr352) Antibody. The lane on the left is treated with antigen-specific peptide.

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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