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Mouse Syk Antibody

Mouse Syk Antibody Mouse Syk Antibody

Instruction Manual!

Product name: Mouse Syk Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Supplied in PBS with 0.09% (W/V) sodium azide.
Applications:WB
Storage:Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
UOM:100ug

Mouse Syk Antibody

Catalog Number:IC285266

Product Profile

Product Name Mouse Syk Antibody
Antibody Type Primary Antibodies
Productdescription
							
							
Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion. Phosphorylates USP25 and regulates its intracellular levels (By similarity).1) Heizmann, B., et al. Proc. Natl. Acad. Sci. U.S.A. 107(43):18563-18568(2010)
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Immunogen
This Mouse Syk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of mouse Syk.

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

WB

For WB starting dilution is: 1:1000:
Species Reactivity

Human

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol Syk
Alternative Names
Tyrosine-protein kinase SYK
Spleen tyrosine kinase
Syk
ptk72
Sykb
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Molecular Weight(MW) 71 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Chicken

Database Links

Entrez Gene 20963
Protein Accession P48025

Application

  • Application

    Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstratedetected the Syk protein (arrow).

Application Notes
For WB starting dilution is: 1:1000:

Additional Information

Form Liquid
StorageInstructions  Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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