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CDKN1B Antibody

CDKN1B Antibody CDKN1B Antibody

Instruction Manual!

Product name: CDKN1B Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Supplied in PBS with 0.09% (W/V) sodium azide.
Applications:IHC-PWB
Storage:Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
UOM:100ug

CDKN1B Antibody

Catalog Number:IC275180

Product Profile

Product Name CDKN1B Antibody
Antibody Type Primary Antibodies
Productdescription
							
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq].1) Kajihara, R., et al. Biochem. Biophys. Res. Commun. 401(3):350-355(2010) Kedde, M., et al. Nat. Cell Biol. 12(10):1014-1020(2010) Canbay, E., et al. Anticancer Res. 30(7):3093-3098(2010) Do Nascimento Borges, B., et al. In Vivo 24(4):579-582(2010) Qin, J., et al. Hepatogastroenterology 57 (99-100), 547-553 (2010) :
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Immunogen
This CDKN1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the C-terminal region of human CDKN1B.

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

IHC-PWB

For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Species Reactivity

Human

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol CDKN1B
Alternative Names
Cyclin-dependent kinase inhibitor 1B
Cyclin-dependent kinase inhibitor p27
p27Kip1
CDKN1B
KIP1
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Molecular Weight(MW) 22 kDa

Database Links

Entrez Gene 1027
Protein Accession P46527

Application

  • Application

    CDKN1B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Application

    Western blot analysis in human normal Uterus tissue lysates (35ug/lane).

Application Notes
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:

Additional Information

Form Liquid
StorageInstructions  Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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