CDKN1B antibody - C-terminal region
Product name: | CDKN1B antibody - C-terminal region |
Source: | Rabbit |
Purity: | >95% |
Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Note: The product is for research use only,not for use in diagnostic or therapeutic procedures. Catalog Number:OM105240 Price:$325.00 Discount Price Size: Store:In stock |
Applications: | WB |
Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
UOM: | 100ug |
Rabbit anti-CDKN1B polyclonal antibody - C-terminal region
Catalog Number:IC121890
Product Profile
ProductName | Rabbit anti-CDKN1B polyclonal antibody - C-terminal region |
---|---|
AntibodyType | Primary Antibodies |
Immunogen |
The immunogen for anti-CDKN1B antibody: synthetic peptide directed towards the C terminal of human CDKN1B |
Key Feature
Clonality | Polyclonal |
---|---|
Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Target Information
Gene Symbol | CDKN1B |
---|---|
Gene Synonyms |
CDKN4
More
KIP1 MEN1B MEN4 P27KIP1 |
Gene Full Name | Cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
Gene Summary |
CDKN1B is a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. It binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
More
|
Alternative Names |
CDKN4
More
KIP1 MEN1B MEN4 P27KIP1 |
MolecularWeight(MW) | 22kDa |
Sequence | 198 amino acids |
Database Links
Entrez Gene | 1027 |
---|---|
SwissProt ID | P46527 |
Protein Accession | NP_004055 |
Application
Additional Information
Form | Liquid |
---|---|
Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.