NMDA NR1 Antibody

Instruction Manual!

Product name:	NMDA NR1 Antibody
Source:	Rabbit
Purity:	>95%
Buffer Formulation:	phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:
Storage:	NMDA NR1 Subunit antibody can be stored at -20˚C. After reconstitution in 50 μl water, the antibody should be aliquot and stored at -20˚C. This product is stable at -20˚C for at least 1 year and can be shipped ambient domestic or international.
UOM:	100ug

NMDA NR1 Antibody

Catalog Number：IC286294

Product Profile

Product Name	NMDA NR1 Antibody
Antibody Type	Primary Antibodies
Productdescription	The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s disease, epilepsy and ischemic neuronal cell death. Increased membrane surface expression of the NR1 subunit of the receptor has been associated with synaptic plasticity.1) Luo, J.H., Wang, Y.H., Yasuda, R.P., Dunah, A.W. and Wolfe, B.B., "The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B)," Mol. Pharmacol. 51 (1997) 79 - 86. More
Immunogen	NMDA NR1 Subunit monoclonal antibody was raised against a fusion protein from AA 1 - 564 of NMDA NR1.

Key Feature

Clonality	Monoclonal
Host Species	Mouse
Concentration	1mg/ml
Purification	Affinity purified

Target Information

Gene Symbol	Grin1
Alternative Names	NR1 GluN1 NMDAR1 Nmdar1 N-methyl-D-aspartate receptor subunit NR1 More
Molecular Weight(MW)	120

Database Links

Entrez Gene	24408
Protein Accession	P35439

Application

Application

NMDA NR1 Subunit Antibody

ApplicationNotes	NMDA NR1 Subunit antibody allows for strong and specific immunolabeling of the 120k NR1 protein in Western blots of rat brain hippocampal homogenate. Applications include Dot Blots (DB), Immunoprecipitation (IP) and Western Blots (WB). Mouse anti-NMDA NR1 Subunit recognizes NR1 in human, mouse and rat brain lysates. When internally tested under ideal conditions the working dilutions were 1:300 for DB and WB, and 3 μg per 200 μg lysate (will quantitatively precipitate all the NMDA NR1 in 200 μg of rat brain lysate).: More

ApplicationNotes

NMDA NR1 Subunit antibody allows for strong and specific immunolabeling of the 120k NR1 protein in Western blots of rat brain hippocampal homogenate. Applications include Dot Blots (DB), Immunoprecipitation (IP) and Western Blots (WB). Mouse anti-NMDA NR1 Subunit recognizes NR1 in human, mouse and rat brain lysates. When internally tested under ideal conditions the working dilutions were 1:300 for DB and WB, and 3 μg per 200 μg lysate (will quantitatively precipitate all the NMDA NR1 in 200 μg of rat brain lysate).:

Form	Liquid
StorageInstructions	NMDA NR1 Subunit antibody can be stored at -20˚C. After reconstitution in 50 μl water, the antibody should be aliquot and stored at -20˚C. This product is stable at -20˚C for at least 1 year and can be shipped ambient domestic or international.
Storage Buffer	phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

NMDA NR1 Antibody

NMDA NR1 Antibody

Product Profile

Key Feature

Target Information

Database Links

Application

Application

Additional Information