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Bax (phospho Thr167) Antibody

Bax (phospho Thr167) Antibody Bax (phospho Thr167) Antibody

Instruction Manual!

Product name: Bax (phospho Thr167) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:IF
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

Bax (phospho Thr167) Antibody

Catalog Number:IC272271

Product Profile

Product Name Bax (phospho Thr167) Antibody
Antibody Type Primary Antibodies
Productdescription
							
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.1) Francesca Andriani. J Natl Cancer Inst, Sep 2001; 93: 1314 - 1324.
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Immunogen
Bax (phospho Thr167) antibody was raised against a peptide sequence around phosphorylation site of threonine167 (P-G-T (p)-P-T) derived from Human Bax.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IF

Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol BAX
Alternative Names
BAXA
Apoptosis regulator BAX
membrane isoform alpha
Bcl2-associated X protein
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MolecularWeight(MW)  21 kDa
Tissue Specificity The antibody detects endogenous levels of Bax only when phosphorylated at threonine 167.

Database Links

Entrez Gene 581
Protein Accession NP_620116.1

Application

  • Application

    Immunofluorescence staining of methanol-fixed A549 cells using Bax (Phospho-Thr167) Antibody.

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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