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ABL1 (phospho Thr735) Antibody

ABL1 (phospho Thr735) Antibody ABL1 (phospho Thr735) Antibody

Instruction Manual!

Product name: ABL1 (phospho Thr735) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

ABL1 (phospho Thr735) Antibody

Catalog Number:IC269637

Product Profile

Product Name ABL1 (phospho Thr735) Antibody
Antibody Type Primary Antibodies
Productdescription 
							
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.1) Fainstein E., Oncogene 4:1477-1481(1989).
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Immunogen
ABL1 (phospho Thr735) antibody was raised against a peptide sequence around phosphorylation site of threonine735 (S-V-T (p)-L-P) derived from Human ABL1.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol ABL1
Alternative Names
Abelson murine leukemia viral oncogene 1
ABL1
c-ABL
JTK7
p150
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MolecularWeight(MW)  135 kDa
Tissue Specificity The antibody detects endogenous levels of ABL1 only when phosphorylated at threonine 735.

Database Links

Entrez Gene 25
Protein Accession NP_005148.2

Application

  • Application

    Western blot analysis of extracts from COS cells treated with EGF using ABL1 (Phospho-Thr735) Antibody. The lane on the right is treated with the antigen-specific peptide.

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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