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Abl (phospho Tyr204) Antibody

Abl (phospho Tyr204) Antibody Abl (phospho Tyr204) Antibody

Instruction Manual!

Product name: Abl (phospho Tyr204) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

Abl (phospho Tyr204) Antibody

Catalog Number:IC269635

Product Profile

Product Name Abl (phospho Tyr204) Antibody
Antibody Type Primary Antibodies
Productdescription 
							
Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 (involved in branch formation); ANXA1 (involved in membrane anchoring); DBN1, DBNL, CTTN, RAPH1 and ENAH (involved in signaling); or MAPT and PXN (microtubule-binding proteins).1) Meyn MA, et al. (2006) J Biol Chem 281, 30907-16
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Immunogen
Abl (phospho Tyr204) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 204 (K-L-Y (p)-V-S) derived from Human c-Abl.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol ABL1
Alternative Names
p150
c-ABL
EC 2.7.10.2
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Molecular Weight(MW) 135 kDa
Tissue Specificity The antibody detects endogenous level of Abl only when phosphorylated at tyrosine 204.

Database Links

Entrez Gene 25
Protein Accession NP_005148.2

Application

  • Application

    Western blot analysis of extracts from COS7 cells treated with Adriamycin using Abl (Phospho-Tyr204) Antibody. The lane on the right is treated with the antigen-specific peptide.

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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