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PTK2B antibody - C-terminal region
Instruction Manual!
| Product name: | PTK2B antibody - C-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Note: The product is for research use only,not for use in diagnostic or therapeutic procedures. Catalog Number:OM105240 Price:$325.00 Discount Price Size: Store:In stock |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-PTK2B polyclonal antibody - C-terminal region
Catalog Number：IC105966
Product Profile
| ProductName | Rabbit anti-PTK2B polyclonal antibody - C-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-PTK2B antibody: synthetic peptide directed towards the C terminal of human PTK2B |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | PTK2B |
|---|---|
| Gene Synonyms |
PKB
More
PTK CAKB FAK2 PYK2 CADTK FADK2 RAFTK |
| Gene Full Name | PTK2B protein tyrosine kinase 2 beta |
| Gene Summary |
PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.
More
|
| Alternative Names |
PKB
More
PTK CAKB FAK2 PYK2 CADTK FADK2 RAFTK |
| MolecularWeight(MW) | 116kDa |
| Sequence | 1009 amino acids |
Database Links
| Entrez Gene | 2185 |
|---|---|
| SwissProt ID | Q14289 |
| Protein Accession | NP_004094 |
Application
-
Western blot
0.2-1 ug/ml
Positive Control: HepG2 cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
