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RSK1/2/3/4 (phospho Ser221/227/S218/232) Antibody

RSK1/2/3/4 (phospho Ser221/227/S218/232) Antibody RSK1/2/3/4 (phospho Ser221/227/S218/232) Antibody

Instruction Manual!

Product name: RSK1/2/3/4 (phospho Ser221/227/S218/232) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WB
Storage:Store antibody at -20˚,C for up to one year.
UOM:100ug

RSK1/2/3/4 (phospho Ser221/227/S218/232) Antibody

Catalog Number:IC290408

Product Profile

Product Name RSK1/2/3/4 (phospho Ser221/227/S218/232) Antibody
Antibody Type Primary Antibodies
Productdescription 
							
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway.1) Moller D.E., Am. J. Physiol. 266:C351-C359(1994).
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Immunogen
RSK1/2/3/4 (phospho Ser221/227/S218/232) antibody was raised against a peptide sequence around phosphorylation site of Serine 221/227/218/232 (A-Y-S (p)-F-C) derived from Human RSK1/2/3/4.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouse

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol RPS6KA1, RPS6KA2, RPS6KA3, RPS6KA6
Alternative Names
KS6A1
KS6AA
MAPKAP-K1a
RSK1
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MolecularWeight(MW)  85 kDa
Tissue Specificity The antibody detects endogenous levels of RSK1/2/3/4 only when phosphorylated at serine 221/227/218/232.

Database Links

Entrez Gene 6195/6197/6196/27330
Protein Accession NP_002944.2

Application

  • Application

    Western blot analysis of extracts from HepG2 cells (Lane 2), using RSK1/2/3/4 (Phospho-Ser221/227/218/232) Antibody. The lane on the left is treated with antigen-specific peptide.

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚,C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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