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Ezrin (phospho Tyr146) Antibody

Ezrin (phospho Tyr146) Antibody Ezrin (phospho Tyr146) Antibody

Instruction Manual!

Product name: Ezrin (phospho Tyr146) Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

Ezrin (phospho Tyr146) Antibody

Catalog Number:IC278348

Product Profile

Product Name Ezrin (phospho Tyr146) Antibody
Antibody Type Primary Antibodies
Productdescription
							
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.1) Murchie R, et al. (2014)Proc Natl Acad Sci U S A 111, 693-8. Kawahara T, et al. (2013)PLoS One 8, e79654 . Wang Y, Lazo JS (2012)Oncogene 31, 818-27.
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Immunogen
Ezrin (phospho Tyr146) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 146 (S-G-Y (p)-L-S) derived from Human Ezrin.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol EZR
Alternative Names
Cytovillin
EZRI
p81
VIL2
Villin 2
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Molecular Weight(MW) 69 kDa
Tissue Specificity The antibody detects endogenous level of Ezrin only when phosphorylated at tyrosine 146.

Database Links

Entrez Gene 7430
Protein Accession NP_001104547.1

Application

  • Application

    Western blot analysis of extracts from 293 cells treated with UV using Phospho-Ezrin (Tyr146) Antibody. The lane on the right is treated with the antigen-specific peptide.

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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