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CALR antibody - middle region
Instruction Manual!
| Product name: | CALR antibody - middle region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-CALR polyclonal antibody - middle region
Catalog Number：IC117822
Product Profile
| ProductName | Rabbit anti-CALR polyclonal antibody - middle region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-CALR antibody: synthetic peptide directed towards the middle region of human CALR |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | CALR |
|---|---|
| Gene Synonyms |
CRT
More
FLJ26680 RO SSA cC1qR |
| Gene Full Name | Calreticulin |
| Gene Summary |
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
More
|
| Alternative Names |
CRT
More
FLJ26680 RO SSA cC1qR |
| MolecularWeight(MW) | 46kDa |
| Sequence | 417 amino acids |
Database Links
| Entrez Gene | 811 |
|---|---|
| SwissProt ID | P27797 |
| Protein Accession | NP_004334 |
Application
-
Western blot
0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human brain
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
