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NFIL3 antibody - middle region
Instruction Manual!
| Product name: | NFIL3 antibody - middle region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-NFIL3 polyclonal antibody - middle region
Catalog Number：IC105274
Product Profile
| ProductName | Rabbit anti-NFIL3 polyclonal antibody - middle region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-NFIL3 antibody: synthetic peptide directed towards the middle region of human NFIL3 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | NFIL3 |
|---|---|
| Gene Synonyms |
E4BP4
More
IL3BP1 NF-IL3A NFIL3A |
| Gene Full Name | Nuclear factor, interleukin 3 regulated |
| Gene Summary |
NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
More
|
| Alternative Names |
E4BP4
More
IL3BP1 NF-IL3A NFIL3A |
| MolecularWeight(MW) | 51kDa |
| Sequence | 462 amino acids |
Database Links
| Entrez Gene | 4783 |
|---|---|
| SwissProt ID | Q16649 |
| Protein Accession | NP_005375 |
Application
-
Western blot
Host: Rabbit
Target Name: NFIL3
Sample Tissue: Human Fetal Brain
Antibody Dilution: 1.0ug/ml -
Western blot
0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human brain
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
