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FGD1 antibody - C-terminal region
Instruction Manual!
| Product name: | FGD1 antibody - C-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-FGD1 polyclonal antibody - C-terminal region
Catalog Number：IC105454
Product Profile
| ProductName | Rabbit anti-FGD1 polyclonal antibody - C-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-FGD1 antibody: synthetic peptide directed towards the C terminal of human FGD1 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | FGD1 |
|---|---|
| Gene Synonyms |
AAS
More
FGDY MRXS16 ZFYVE3 |
| Gene Full Name | FYVE, RhoGEF and PH domain containing 1 |
| Gene Summary |
FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.
More
|
| Alternative Names |
AAS
More
FGDY MRXS16 ZFYVE3 |
| MolecularWeight(MW) | 107kDa |
| Sequence | 961 amino acids |
Database Links
| Entrez Gene | 2245 |
|---|---|
| SwissProt ID | P98174 |
| Protein Accession | NP_004454 |
Application
-
Western blot
0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Raji cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
