c-Kit Antibody PE
Product name: | c-Kit Antibody PE |
Source: | Mouse |
Purity: | >95% |
Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Applications: | WBIPIFFCELISA |
Storage: | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
UOM: | 100ug |
c-Kit Antibody PE
Catalog Number:IC194026
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Product Profile
Product Name | c-Kit Antibody PE |
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Antibody Type | Primary Antibodies |
ModificationNotes | The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers. |
Key Feature
Clonality | Monoclonal |
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Isotype | IgG1 |
Host Species | Mouse |
Tested Applications | |
recommended for detection of c-Kit of human origin by WB, IP, IF, FCM and ELISA:
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Species Reactivity | |
Concentration | 100 tests in 2 ml |
Purification | Affinity purified |
Target Information
Alternative Names |
raised against full length c-Kit of human origin
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Tissue Specificity | raised against full length c-Kit of human origin |
Database Links
Entrez Gene | 3815 |
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Application
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Application
Western blot analysis of c-Kit expression in HEL 92.1.7 (A) and TT (B) whole cell lysates.
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Application
FCM analysis of TF-1 cells. Black line histogram represents the isotype control, normal mouse IgG1: .
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Application
Immunofluorescence staining of methanol-fixed TF-1 cells showing membrane staining.
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Application
Western blot analysis of c-Kit expression in CCRF-HSB-2 (A) and HEL 92.1.7 (B) whole cell lysates.
Application Notes |
recommended for detection of c-Kit of human origin by WB, IP, IF, FCM and ELISA:
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Additional Information
Form | Liquid |
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StorageInstructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.