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MART-1/Melan-A Antibody (C-term) (Ascites)

MART-1/Melan-A Antibody (C-term) (Ascites) MART-1/Melan-A Antibody (C-term) (Ascites)

Instruction Manual!

Product name: MART-1/Melan-A Antibody (C-term) (Ascites)
Source:Mouse
Purity:>95%
Buffer Formulation:Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Applications:WB
Storage:For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
UOM:100ug

MART-1/Melan-A Antibody (C-term) (Ascites)

Catalog Number:IC213317

Product Profile

Product Name MART-1/Melan-A Antibody (C-term) (Ascites)
Antibody Type Primary Antibodies

Key Feature

Clonality Monoclonal
Isotype IgG1
Clone Number 610CT14.6.4
Host Species Mouse
Tested Applications

WB

WB~~1:100~1600:
Species Reactivity

Human

Concentration 1mg/ml
Purification

Target Information

Gene Synonyms
MART1
Alternative Names
MLANA
MART1
Melanoma antigen recognized by T-cells 1
Antigen LB39-AA
Antigen SK29-AA
Protein Melan-A
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MolecularWeight(MW)  13157 Da
Function
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes
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Tissue Specificity Expression is restricted to melanoma and melanocyte cell lines and retina
Cellular Localization Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Note=Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post- Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation

Database Links

Entrez Gene 2315
Nucleotide Accession NP_005502

Application

  • Application

    MART-1/Melan-A Antibody (C-term)(Ascites)(Cat. #AM2133a) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the MART-1/Melan-A antibody detected the MART-1/Melan-A protein (arrow).

Application Notes
WB~~1:100~1600:

Additional Information

Form Liquid
StorageInstructions  For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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