MART-1/Melan-A Antibody (C-term) (Ascites)
Product name: | MART-1/Melan-A Antibody (C-term) (Ascites) |
Source: | Mouse |
Purity: | >95% |
Buffer Formulation: | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
Applications: | WB |
Storage: | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
UOM: | 100ug |
MART-1/Melan-A Antibody (C-term) (Ascites)
Catalog Number:IC213317
Product Profile
Product Name | MART-1/Melan-A Antibody (C-term) (Ascites) |
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Antibody Type | Primary Antibodies |
Key Feature
Clonality | Monoclonal |
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Isotype | IgG1 |
Clone Number | 610CT14.6.4 |
Host Species | Mouse |
Tested Applications | |
WB~~1:100~1600:
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Species Reactivity | |
Concentration | 1mg/ml |
Purification |
Target Information
Gene Synonyms |
MART1
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Alternative Names |
MLANA
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MART1 Melanoma antigen recognized by T-cells 1 Antigen LB39-AA Antigen SK29-AA Protein Melan-A |
MolecularWeight(MW) | 13157 Da |
Function |
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes
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Tissue Specificity | Expression is restricted to melanoma and melanocyte cell lines and retina |
Cellular Localization | Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Note=Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post- Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation |
Database Links
Entrez Gene | 2315 |
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Nucleotide Accession | NP_005502 |
Application
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Application
MART-1/Melan-A Antibody (C-term)(Ascites)(Cat. #AM2133a) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the MART-1/Melan-A antibody detected the MART-1/Melan-A protein (arrow).
Application Notes |
WB~~1:100~1600:
|
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Additional Information
Form | Liquid |
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StorageInstructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.