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MCL-1 Antibody
Instruction Manual!
| Product name: | MCL-1 Antibody |
| Source: | Mouse |
| Purity: | >95% |
| Buffer Formulation: | Purified recombinant fragment of human MCL-1 expressed in E. Coli. |
| Applications: | WBIHCIF |
| Storage: | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| UOM: | 100ug |
MCL-1 Antibody
Catalog Number：IC213415
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Product Profile
| Product Name | MCL-1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
Key Feature
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 8C6, 8C6D4B1 |
| Host Species | Mouse |
| Tested Applications | |
|
WB~~1:500 - 2000. IHC~~1:200 - 1000. IF~~1:200 - 1000.:
|
|
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification |
Target Information
| Gene Synonyms |
BCL2L3
|
|---|---|
| Alternative Names |
EAT
More
MCL1L MCL1S |
| MolecularWeight(MW) | 37337 Da |
| Function |
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis Isoform 2 promotes apoptosis
More
|
| Tissue Specificity | Purified recombinant fragment of human MCL-1 expressed in E. Coli. |
| Cellular Localization | Membrane; Single-pass membrane protein (Potential). Cytoplasm. Mitochondrion. Nucleus, nucleoplasm Note=Cytoplasmic, associated with mitochondria |
Database Links
| Entrez Gene | 4170 |
|---|---|
| Nucleotide Accession | NP_877495.1 |
Application
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Application
Figure 1: Western blot analysis using anti-MCL1 mAb against Hela (1), BCBL-1 (2), Jurkat (3) and HL60 (4) cell lysate.
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Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human lymphnode tissues using anti-MCL1 mAb with DAB staining.
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Application
Figure 3: Confocal immunofluorescence analysis of HepG2 cells using anti-MCL1 mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
| Application Notes |
WB~~1:500 - 2000. IHC~~1:200 - 1000. IF~~1:200 - 1000.:
|
|---|
Additional Information
| Form | Liquid |
|---|---|
| StorageInstructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human MCL-1 expressed in E. Coli. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
