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MAP3K11 Antibody (ascites)
Instruction Manual!
| Product name: | MAP3K11 Antibody (ascites) |
| Source: | Mouse |
| Purity: | >95% |
| Buffer Formulation: | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Applications: | WB |
| Storage: | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| UOM: | 100ug |
MAP3K11 Antibody (ascites)
Catalog Number：IC213148
Product Profile
| Product Name | MAP3K11 Antibody (ascites) |
|---|---|
| Antibody Type | Primary Antibodies |
Key Feature
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | 230CT5.3.1 |
| Host Species | Mouse |
| Tested Applications | |
|
WB~~1:100~500:
|
|
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification |
Target Information
| Gene Synonyms |
MLK3
More
PTK1 SPRK |
|---|---|
| Alternative Names |
MAP3K11
More
MLK3 PTK1 SPRK Mitogen-activated protein kinase kinase kinase 11 Mixed lineage kinase 3 Src-homology 3 domain-containing proline-rich kinase |
| MolecularWeight(MW) | 92688 Da |
| Function |
Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7 Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle
More
|
| Tissue Specificity | Expressed in a wide variety of normal and neoplastic tissues including fetal lung, liver, heart and kidney, and adult lung, liver, heart, kidney, placenta, skeletal muscle, pancreas and brain |
| Cellular Localization | Cytoplasm, cytoskeleton, centrosome. Note=Location is cell cycle dependent |
Database Links
| Entrez Gene | 4296 |
|---|---|
| Nucleotide Accession | NP_002410.1 |
Application
-
Application
MAP3K11 (Cat. #AM1906a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MAP3K11 antibody detected the MAP3K11 protein (arrow).
| Application Notes |
WB~~1:100~500:
|
|---|
Additional Information
| Form | Liquid |
|---|---|
| StorageInstructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
