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MYST1 Antibody

MYST1 Antibody MYST1 Antibody

Instruction Manual!

Product name: MYST1 Antibody
Source:Mouse
Purity:>95%
Buffer Formulation:Purified recombinant fragment of human MYST1 expressed in E. Coli.
Applications:WBIHCIF
Storage:For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
UOM:100ug

MYST1 Antibody

Catalog Number:ic214932

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Product Profile

Product Name MYST1 Antibody
Antibody Type Primary Antibodies

Key Feature

Clonality Monoclonal
Isotype IgG2b
Clone Number 8C4C4
Host Species Mouse
Tested Applications

WBIHCIF

WB~~1:500 - 2000. IHC~~1:200 - 1000. IF~~1:200 - 1000.:
Species Reactivity

Human

Concentration 1mg/ml
Purification

Target Information

Gene Synonyms
MOF
MYST1
Alternative Names
MOF
KAT8
hMOF
More 
MolecularWeight(MW)  52403 Da
Function
Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex
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Tissue Specificity Purified recombinant fragment of human MYST1 expressed in E. Coli.
Cellular Localization Nucleus. Chromosome (By similarity).

Database Links

Entrez Gene 84148
Nucleotide Accession NP_892003.2

Application

  • Application

    Figure 1: Western blot analysis using anti-MYST1 mAb against Hela (1), HepG2 (2) and SMMC-7721 (3) cell lysate.

  • Application

    Figure 2: Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), normal esophagus epithelium (B), rectum adenocarcinoma (C), lung squamous cell carcinoma (D), breast infiltrating carcinoma (E), and breast infiltrating carcinoma (F) tissues, showing nuclear localization using anti MOF/MYST1 mAb with DAB staining.

  • Application

    Figure 3: Confocal immunofluorescence analysis of Eca 109 cells using anti-MOF/MYST1 mAb (green), showing nuclear localization.

Application Notes
WB~~1:500 - 2000. IHC~~1:200 - 1000. IF~~1:200 - 1000.:

Additional Information

Form Liquid
StorageInstructions  For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified recombinant fragment of human MYST1 expressed in E. Coli.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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