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NKX3A Antibody
Instruction Manual!
| Product name: | NKX3A Antibody |
| Source: | Mouse |
| Purity: | >95% |
| Buffer Formulation: | Purified recombinant fragment of human NKX3A expressed in E. Coli. |
| Applications: | WB |
| Storage: | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| UOM: | 100ug |
NKX3A Antibody
Catalog Number：IC215405
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Product Profile
| Product Name | NKX3A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
Key Feature
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Clone Number | 4H4 |
| Host Species | Mouse |
| Tested Applications | |
|
WB~~1:500 - 2000. IHC~~1:200 - 1000. FC~~1:200 - 400.:
|
|
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification |
Target Information
| Gene Synonyms |
NKX3.1
NKX3A |
|---|---|
| Alternative Names |
NKX3
More
BAPX2 NKX3A NKX3.1 NKX3-1 |
| MolecularWeight(MW) | 26350 Da |
| Function |
Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells
More
|
| Tissue Specificity | Highly expressed in the prostate and, at a lower level, in the testis |
| Cellular Localization | Nucleus. |
Database Links
| Entrez Gene | 4824 |
|---|---|
| Nucleotide Accession | NP_006158.2 |
Application
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Application
Figure 1: Western blot analysis using NKX3A mouse mAb against LNCaP (1) cell lysate.
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Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human prostata tissues (A, B) using anti-NKX3A antibody with DAB staining.
-
Application
Figure 3: Flow cytometric analysis of PC-3 cells using anti-NKX3A mAb (green) and negative control (purple).
| Application Notes |
WB~~1:500 - 2000. IHC~~1:200 - 1000. FC~~1:200 - 400.:
|
|---|
Additional Information
| Form | Liquid |
|---|---|
| StorageInstructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human NKX3A expressed in E. Coli. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
