NOTCH3 Antibody (C-term Q2306) (Ascites)
Product name: | NOTCH3 Antibody (C-term Q2306) (Ascites) |
Source: | Mouse |
Purity: | >95% |
Buffer Formulation: | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
Applications: | WB |
Storage: | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
UOM: | 100ug |
NOTCH3 Antibody (C-term Q2306) (Ascites)
Catalog Number:IC215527
Product Profile
Product Name | NOTCH3 Antibody (C-term Q2306) (Ascites) |
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Antibody Type | Primary Antibodies |
Key Feature
Clonality | Monoclonal |
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Isotype | IgG1 |
Clone Number | 487CT6.9.2 |
Host Species | Mouse |
Tested Applications | |
WB~~1:100~1600:
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Species Reactivity | |
Concentration | 1mg/ml |
Purification |
Target Information
Alternative Names |
NOTCH3
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Neurogenic locus notch homolog protein 3 Notch 3 extracellular truncation Notch 3 intracellular domain |
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MolecularWeight(MW) | 243631 Da |
Function |
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity)
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Tissue Specificity | Ubiquitously expressed in fetal and adult tissues |
Cellular Localization | Cell membrane; Single-pass type I membrane protein |
Database Links
Entrez Gene | 4854 |
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Nucleotide Accession | NP_000426.2 |
Application
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Application
NOTCH3 Antibody (Q2306) (Cat. #AM2059a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the NOTCH3 antibody detected the NOTCH3 protein (arrow).
Application Notes |
WB~~1:100~1600:
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Additional Information
Form | Liquid |
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StorageInstructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.