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NOTCH3 Antibody (C-term Q2306) (Ascites)

NOTCH3 Antibody (C-term Q2306) (Ascites) NOTCH3 Antibody (C-term Q2306) (Ascites)

Instruction Manual!

Product name: NOTCH3 Antibody (C-term Q2306) (Ascites)
Source:Mouse
Purity:>95%
Buffer Formulation:Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Applications:WB
Storage:For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
UOM:100ug

NOTCH3 Antibody (C-term Q2306) (Ascites)

Catalog Number:IC215527

Product Profile

Product Name NOTCH3 Antibody (C-term Q2306) (Ascites)
Antibody Type Primary Antibodies

Key Feature

Clonality Monoclonal
Isotype IgG1
Clone Number 487CT6.9.2
Host Species Mouse
Tested Applications

WB

WB~~1:100~1600:
Species Reactivity

Human

Concentration 1mg/ml
Purification

Target Information

Alternative Names
NOTCH3
Neurogenic locus notch homolog protein 3
Notch 3 extracellular truncation
Notch 3 intracellular domain
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MolecularWeight(MW)  243631 Da
Function
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity)
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Tissue Specificity Ubiquitously expressed in fetal and adult tissues
Cellular Localization Cell membrane; Single-pass type I membrane protein

Database Links

Entrez Gene 4854
Nucleotide Accession NP_000426.2

Application

  • Application

    NOTCH3 Antibody (Q2306) (Cat. #AM2059a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the NOTCH3 antibody detected the NOTCH3 protein (arrow).

Application Notes
WB~~1:100~1600:

Additional Information

Form Liquid
StorageInstructions  For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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