CSEN antibody - N-terminal region
Product name: | CSEN antibody - N-terminal region |
Source: | Rabbit |
Purity: | >95% |
Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Applications: | WBIHC |
Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
UOM: | 100ug |
Rabbit anti-CSEN polyclonal antibody - N-terminal region
Catalog Number:IC105544
Product Profile
ProductName | Rabbit anti-CSEN polyclonal antibody - N-terminal region |
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AntibodyType | Primary Antibodies |
Immunogen |
The immunogen for anti-CSEN antibody: synthetic peptide directed towards the N terminal of human CSEN |
Key Feature
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Target Information
Gene Symbol | CSEN |
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Gene Synonyms |
CSEN
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DREAM KCHIP3 |
Gene Full Name | Kv channel interacting protein 3, calsenilin |
Gene Summary |
CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
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Alternative Names |
CSEN
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DREAM KCHIP3 |
MolecularWeight(MW) | 29kDa |
Sequence | 256 amino acids |
Database Links
Entrez Gene | 30818 |
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SwissProt ID | Q9Y2W7 |
Protein Accession | NP_038462 |
Application
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Western blot
0.2-1 ug/ml
Positive Control: Jurkat cell lysate -
Immunohistochemical
Additional Information
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.