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SMAD4 antibody - middle region
Instruction Manual!
| Product name: | SMAD4 antibody - middle region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-SMAD4 polyclonal antibody - middle region
Catalog Number：IC105590
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Product Profile
| ProductName | Rabbit anti-SMAD4 polyclonal antibody - middle region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-SMAD4 antibody: synthetic peptide directed towards the middle region of human SMAD4 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Protein A |
Target Information
| Gene Symbol | SMAD4 |
|---|---|
| Gene Synonyms |
JIP
More
DPC4 MADH4 MYHRS |
| Gene Full Name | SMAD family member 4 |
| Gene Summary |
SMAD4 is one of the Smad family members, which are essential intracellular signalling components of the transforming growth factor-beta (TGF-beta) superfamily. Smad2 and Smad3 are structurally highly similar and mediate TGF-beta signals. Smad4 is distantly related to Smads 2 and 3, and forms a heteromeric complex with Smad2 after TGF-beta or activin stimulation. TGF-beta induces heteromeric complexes of Smads 2, 3 and 4, and their concomitant translocation to the nucleus, which is required for efficient TGF-beta signal transduction
More
|
| Alternative Names |
JIP
More
DPC4 MADH4 MYHRS |
| MolecularWeight(MW) | 60kDa |
| Sequence | 552 amino acids |
Database Links
| Entrez Gene | 4089 |
|---|---|
| SwissProt ID | Q13485 |
| Protein Accession | NP_005350 |
Application
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Western blot
SMAD4 antibody - middle region validated by WB using U2OS nuclear extracts
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Western blot
Sample Type: Human nuclear cell extracts (30ug)
Primary Dilution: 1:1000
Secondary Antibody: anti-Rabbit HRP
Secondary Dilution: 1:20000
Image Submitted By: Katarina Luciakova
Cancer Research Institute See Customer Feedback tab for detailed information. -
Western blot
1.25ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
